tina huang data scientist

Nat. This results in a tree with 57 newly reported and previously published ancient individuals while present-day sequences are collapsed in the major Y-chromosome haplogroups (the most basal lineages are not shown). . To determine the Y-chromosome haplogroups of male individuals, we genotyped the Y-chromosome reads using a Y-SNP list (v.15.73) from the International Society of Genetic Genealogy (ISOGG) dataset, ignoring C-to-T and G-to-A transitions on the forward and reverse reads, respectively. 25, 459466 (2015). One of my favorite videos of her is where she talks about the resume that got her an entry-level data science job. Survival of Late Pleistocene hunter-gatherer ancestry in the Iberian Peninsula. Hi! ScienceDaily. We show that all analysed Epigravettian-associated individuals carry a homogeneous Villabruna ancestry, with the intra-group genetic structure mainly determined by their geographical, and not temporal, distribution. Nakatsuka, N. et al. Straus, L. G. The human occupation of southwestern Europe during the Last Glacial Maximum: Solutrean cultural adaptations in France and Iberia. Graduate - February 2015 to September 2015. Tina started her YouTube channel in 2020. Then the cleaned reads together with cleaned reads from 1240k capture sequencing were mapped to human reference mitochondrial sequence NC_012920.1 with BWA 0.7.12 aln/samse algorithm (parameters n 0.01, l 16500) and realigned with CircularMapper64. 864358 (to K.M. The PCA was calculated with 1379 individuals from 87 western Eurasian modern populations on the 1240k_HO dataset, which was intersected between the 1240k and Human Origins datasets (Supplementary Data 1.K). This research aims to determine whether a neural response telemetry (NRT) threshold determines the success of surgery. Some of those early groups from more than 40ka further admixed with Neanderthals, as shown by signals of recent introgression in individuals from Bacho Kiro in Bulgariaassociated with an Initial Upper Palaeolithic (IUP) archaeological cultureand from Petera cu Oase in Romania2,6. The increasing level of admixture between distinct hunter-gatherer populations from around 8ka onwards indicates an intensified mobility of those forager groups. 14 following. Article We also genotyped a selection of previously published individuals with the same approach (Supplementary Data 1.G)2,4,30,74,75,76,77,78. Unlike setting up a Premium subscription to our platform, for which you would be billed monthly or annually, acquiring individual courses requires a one-time payment only. This often involves analyzing similar products to compare how they performed. Product development is, by far, my favorite data science use case for two main reasons. I'm interested in tech, trading, and how to minimize effort and maximize outcome. Save my name, email, and website in this browser for the next time I comment. HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing. Greater San Diego Area. 13, 24472461 (2018). Extended Data Fig. Evol. Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers. Its not just the top 200 that this competition attracts, but anyone interested in data science. Gravettian cranial morphology and human group affinities during the European Upper Palaeolithic. Details of the modelling are provided in Supplementary Data 3.E,F. Cassidy, L. M. et al. Huang, Y. This broadly distributed ancestry (the Oberkassel cluster (also known as WHG)) is most closely related to an Epigravettian-associated individual from northwestern Italy, suggesting that its expansion into continental Europe might have started from the westand not the eastside of the Alps. Become the most confident candidate in the room. Data warehousing is a relatively new field that focuses on the use of large datasets for analytical purposes. Second, the ancestry of individuals associated with the Epigravettian culture (Villabruna cluster), which was found to genetically connect European and Near Eastern hunter-gatherers, reached southern Europe well before the transition between the Early and Late Epigravettian4,15 and possibly as early as the GravettianEpigravettian transition. Fu, Q. et al. About me. CAS Genome Biol. These results show that some, but not all, of the genomic ancestries present in Europe between around 40ka and 30ka survived in the Gravettian-associated populations studied so far. Mathieson, I. et al. Lead Advisor - Data Science. Biotechniques 59, 8793 (2015). By contrast, the Goyet Q116-1 genetic profile gave rise to the newly described Fournol cluster identified in Gravettian-associated individuals from western and southwestern Europe. Hunter-gatherers across the great Adriatic-Po region during the Last Glacial Maximum: environmental and cultural dynamics. She supports Propel on the business and marketing side. Biol. Google Scholar. 4. Remember, its the problem that defines the tools we use! In each of the past 200 years they have only seen four new entrants into their top 200 list. F-statistics suggest that Le Piage II is genetically intermediate between Fournol 85 and El Mirn (Supplementary Data 2.D). Bioinformatics 38, 37683777 (2022). Previous studies have shown that two main hunter-gatherer ancestries were predominant across most parts of Europe after around 14kathat is, the western hunter-gatherer (WHG) ancestry, related to the Villabruna cluster, and the eastern hunter-gatherer (EHG) ancestry, showing affinity to both the Villabruna and the ancient north Eurasian (ANE) ancestry found in Upper Palaeolithic Siberian individuals4,36. Xiamen Guansheng Precision Machinery Co Ltd is a company integrating R&D, production and sales. Rohrlach, A. You'll likely won't meet her on a day to day basis, but she's always lurking in the Discord and following everybody's progress (not . J. Archaeol. After 2 washing steps using the manufacturers wash buffer, DNA was eluted in TET (10mM Tris, 1mM EDTA and 0.05% Tween) in two steps for a final volume of 100l. A dashed line of 50 cM total ROH is drawn in each panel to help comparison between panels with different y-axis scales. In the MDS plot, we find that all of the newly and previously reported Epigravettian-associated individuals fall within the Villabruna cluster4 (Fig. Nature 615, 117126 (2023). This button displays the currently selected search type. Nucleic Acids Res. Oxidation of methane into valuable chemicals, such as C 2+ molecules, has been long sought after but the dilemma between high yield and high selectivity of desired products remains. 3.Tina Huang. Djindjian, F. Territories and economies of hunter-gatherer groups during the last glacial maximum in Europe. She graduated with a degree in Computer Science and Applied Math. Our capabilities include CNC machining, sheet metal & Banks, W. E. in Les Socits Gravettiennes du Nord-Ouest Europen: Nouveaux Sites, Nouvelles Donnes, Nouvelles Lectures (eds Touz, O., Goutas, N., Salomon, H. & Noiret, P.) 323266 (Presses Univ. 17, 60 (2016). Skoglund, P. et al. Were dedicated to providing you the best ofNews, with a focus on dependability andBusiness. In her journey of eventually. Check out Do Deepfakes Have Fingerprints? Most data scientists are used to having to do the dirty work of cleaning and cleansing data. Kozowski, S. K., Potowicz-Bobak, M., Bobak, D. & Terberger, T. New information from Maszycka Cave and the Late Glacial recolonisation of Central Europe. Subsequently, I worked in . Science 328, 710722 (2010). Teaching Assistant. A high-coverage genome sequence from an archaic Denisovan individual. Article The MDS analysis showing the genetic affinity among European hunter-gatherers was based on the distance matrix derived from outgroup f3-statistics, in the form 1f3(Mbuti.DG; pop1, pop2) and performed with classical MDS algorithm (cmdscale) implemented in R 3.5.1. Edgar, R. C. MUSCLE: multiple sequence alignment with high accuracy and high throughput. This process allowed us to assign an ancestral or derived haplogroup for covered branches, and to make corrections to calls in cases where, for instance, a more derived haplogroup was called because of residual ancient damage (C-to-T or G-to-A mismatches) in terminal read positions at diagnostic SNPs98 (Supplementary Data 1.A). Her first stepping stone into data science was being a research assistant in Bioinformatics. Sci. 771234-PALEoRIDER (to W.H. Late Upper Palaeolithic hunter-gatherers in the Central Mediterranean: new archaeological and genetic data from the Late Epigravettian burial Oriente C (Favignana, Sicily). 4. The effective population sizes (Ne) were then estimated using a maximum likelihood method, after filtering individuals with a signal of close-kin inbreeding (individuals with at least 50 cM of their genome in ROH spanning >20 cM) (Supplementary Information, section9). The inferred pattern of short ROH (48 cM, visualized in blue) being common is in stark contrast to most later farmer populations, where the majority of individuals have no short ROH whatsoever (see101), and evidences small effective population sizes across West Eurasian hunter-gatherer groups. Maier, A. The Solutrean culture is temporally intermediate between the Gravettian and the Magdalenian (or the Badegoulian) cultures, and is found in southwestern and western Europe, which are considered to have been climatic refugia for human populations during the LGM25,26. All individuals belonging to the Fournol cluster show higher affinity to Goyet Q116-1 than to the Sunghir group (n=4), and the Vstonice-cluster individuals show higher affinity to the Sunghir group than to Goyet Q116-1 (Extended Data Fig. The colours correspond to the grouping of tested populations, dots refer to the f4-values and the dark and light error bars to 1*SE and 3*SE estimated from 5 cM block jackknife, respectively. Ancient genomes from present-day France unveil 7,000 years of its demographic history. My name is Tina Huang and I'm a data scientist at a FAANG company. iScience 25, 104244 (2022). b, Calibrated radiocarbon dates of individuals plotted in a. The Kostenki (and Sunghir group) ancestry contributed to the previously described Vstonice cluster represented by Gravettian-associated individuals from central-eastern and southern Europe4. and D.C. have received funding from the Italian Ministry of University and Research (MUR) PRIN 2017 grants 20177PJ9XF and 20174BTC4R_002. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. Nucleic Acids Res. Dashed lines show the frequencies estimated for the indicatedpresent-day 1000 GenomesProject populations (CEU, Utah residents of northern and westernEuropean ancestry; GBR, British; IBS, Spanish;TSI,Tuscan)37. Join now Sign in . Narasimhan, V. M. et al. de Investigacin en Arqueologa y Patrimonio Histrico, University of Alicante, Sant Vicent del Raspeig, Alicante, Spain, Javier Fernndez-Lpez de Pablo&Magdalena Gmez-Puche, Amsterdam Centre of Ancient Studies and Archaeology, University of Amsterdam, Amsterdam, The Netherlands, Department of Anatomy, Histology and Anthropology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania, Service Rgional de lArchologie de Bourgogne-Franche-Comt, Besanon Cedex, France, Laboratoire de Chrono-Environnement, UMR 6249 du CNRS, UFR des Sciences et Techniques, Besanon Cedex, France, Institute of Pre- and Protohistory, University of Tbingen, Tbingen, Germany, Department of Archeological Sciences, Thuringian State Office for Monuments Preservation and Archeology, Weimar, Germany, University of Bucharest, Faculty of Geology and Geophysics, Department of Geology, Bucharest, Romania, Institute for Advanced Studies in Levant Culture and Civilization, Bucharest, Romania, German Archaeological Institute, Berlin, Germany, Brandenburg Authorities for Heritage Management and Archaeological State Museum, Zossen, Germany, Institute for Pre- and Protohistory, Kiel University, Kiel, Germany, Institute of Archeology at Brno, Czech Academy of Sciences, Centre for Palaeolithic and Paleoanthropology, Brno, Czechia, Institute of Archaeology, Academy of Sciences of the Republic of Tatarstan, Kazan, Russia, Samara State University of Social Sciences and Education, Samara, Russia, Early Prehistory and Quaternary Ecology, Department of Geosciences, University of Tbingen, Tbingen, Germany, Paleoanthropology, Institute for Archaeological Sciences, Department of Geosciences, University of Tbingen, Tbingen, Germany, DFG Centre for Advanced Studies Words, Bones, Genes, Tools, University of Tbingen, Tbingen, Germany, Royal Belgian Institute of Natural Sciences, Brussels, Belgium, Institute of Archaeology Russian, Academy of Sciences, Moscow, Russia, School of Archaeology, University of Oxford, Oxford, UK, Peter the Great Museum of Anthropology and Ethnography (Kunstkamera), Russian Academy of Sciences, Saint Petersburg, Russia, Department of Cultures, University of Helsinki, Helsinki, Finland, Seminar for Pre- and Protohistory, Gttingen University, Gttingen, Germany, Lower Saxony State Service for Cultural Heritage, Hannover, Germany, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, You can also search for this author in This channel is about data science, learning, and productivity. 41 Year Olds. The long-lasting genetic continuity in Iberia is also reflected in the preservation until the Mesolithic of Y-chromosome haplogroup C, which was predominant in pre-LGM groups but rarely found after the LGM in other parts of Europe (Extended Data Figs. Her advice appears very solid, and she knows about the difficulties and barriers students are faced often when preparing for job interviews. All Rights Reserved. Genome Res. Theyre both important sub-tasks for data scientists to master, but big data data warehousing and data science are only two components of the larger data science endeavor. In addition, those groups also carry affinity to ANF suggesting more complex genetic processes behind their demographic history16. Search 210,843,632 papers from all fields of science. At the same time, these two groups started mixing with each other, and continued to do so for around 3,000 years," Krause says. A recent bottleneck of Y chromosome diversity coincides with a global change in culture. This suggests that between the Early/Middle and Late Gravettian there was an east-to-west expansion of the Vstonice-associated ancestry that reached central-western Europe and created a longitudinal admixturecline between those two genetically distinct pre-LGM populations.

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